On 07th January 2020, Pakistan International Airlines flight No PIA301, Aircraft B77L, Reg No APBGY was operating from Islamabad to Karachi (OPIS – OPKC) on route Islamabad – Hangu – Nawabshah (NH) – Karachi. PIA301 was cleared to descend from FL400 to FL180 on pilot discretion by Area Radar Controller East Karachi. After few minutes Area Radar Controller East realized the close proximity of a reciprocal traffic Emirates Airline, Flight No UAE516, aircraft B77W, Reg no A6EPS operating from Dubai to Delhi (OMDB–VIDP) & maintaining FL350. The controller tried to take evasive action by assigning radar vectors / headings to both the flights, however both (PIA301 and UAE516) received Traffic Collision Avoidance System – Resolution Advisory (TCAS – RA) near Nawabshah and initiated climb and descend respectively. PIA301 climbed to FL369 and UAE516 descended to FL347 due to TCAS – RA.